This article highlights top high-efficiency (HE) laundry detergents designed to fight odors, remove stains, and keep fabrics feeling fresh. Each pick is compatible with HE machines and offers concentrated cleaning power for everyday loads and tougher laundry days. Below, you’ll find detailed product sections and a practical buying guide to help you compare scent, performance, and value across popular brands.
| Product | Brand | Size / Loads | Key Benefit |
|---|---|---|---|
| ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst | Arm & Hammer | 166.5 fl oz / 128 loads | Odor blasting with baking soda and OxiClean |
| Gain + Odor Defense Liquid Laundry Detergent | Gain | 107 loads | 3-in-1 odor defense and freshness |
| ARM & HAMMER Clean Burst Liquid Laundry Detergent | Arm & Hammer | 170 fl oz / 170 loads | Deep cleaning with baking soda blend |
| Tide Original Scent Liquid Laundry Detergent | Tide | 64 loads | Strong stain removal and concentrated power |
| Gain Original Scent Liquid Laundry Detergent | Gain | 154 fl oz / 107 loads | Long-lasting freshness with fragrance release |
ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst

Brand: Arm & Hammer. This HE liquid laundry detergent combines baking soda with OxiClean stain fighters to deeply clean fabrics while targeting tough odors. The Fresh Burst scent aims to leave garments smelling clean and refreshed after each wash. It is advertised to clean 128 medium loads per 166.5 fl oz bottle when used as directed, delivering a multi-benefit clean that enhances fabric brightness and freshness.
Gain + Odor Defense Liquid Laundry Detergent

Brand: Gain. This HE-compatible detergent emphasizes “Odor Defense” with a Super Fresh Blast fragrance. It’s designed to tackle tough odors while delivering a clean and lasting scent. The formula is positioned as a 3-in-1 solution that cleans, deodorizes, and provides a coordinated scent profile when paired with other Gain Plus Odor Defense products.
ARM & HAMMER Clean Burst Liquid Laundry Detergent

Brand: Arm & Hammer. This 170-load HE detergent blends baking soda for deep cleaning and odor control. It emphasizes stain fighting power and fabric care, making it suitable for a wide range of everyday laundry tasks. The concentrated formula aims to deliver strong performance in a smaller amount of product per load.
Tide Original Scent Liquid Laundry Detergent

Brand: Tide. Tide’s Original Scent liquid detergent is engineered for strong stain removal and concentrated cleaning power. It’s designed to handle a broad range of common stains and odors while delivering a robust clean in HE machines, helping keep colors bright and whites clear over many washes.
Gain Original Scent Liquid Laundry Detergent

Brand: Gain. This detergent uses fragrance capsules that release over time to provide lasting freshness. It combines strong cleaning with odor-fighting properties and a classic scent profile, suited for households seeking a recognizable, long-lasting fragrance with reliable cleaning performance in HE washers.
Buying Guide: Key Purchase Considerations
Purpose and fragrance preferences: Select a formula that matches odor control needs and desired scent intensity. Odor-focused blends (like Gain Odor Defense or Arm & Hammer with Odoxi) are ideal for gym wear or active households, while classic fresh scents suit everyday laundry.
Concentration and load size: Higher-load bottles (170 fl oz or more) offer more loads per bottle, often at a lower cost per load. Consider your typical laundry volume when choosing between 64, 107, or 170 loads.
HE compatibility and efficiency: All listed products are designed for high-efficiency machines. Check the label for exact guidance on load size and water usage to maximize efficiency and fabric care.
Stain removal vs. odor control: If you face stubborn stains, prioritize detergents with strong stain-fighting claims (e.g., OxiClean-boosted variants). For persistent odors, look for odor-defending formulas and longer-lasting freshness capsules.
Fabric care and skin considerations: Blends with baking soda are common in Arm & Hammer detergents for odor control and deep cleaning. If sensitive skin is a concern, review any fragrance intensity or potential allergen ingredients before purchasing.
Cost per load and packaging: Compare price per load by dividing the bottle size by the number of loads. While certain scents and boosters drive upfront cost, long-term savings often come from larger, concentrated bottles.
Brand family and compatibility: Some brands offer coordinated scent lines (for example, Gain Plus Odor Defense products) that let you mix and match detergents with a consistent fragrance profile across products such as fabric softeners and boosters.